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Intestinal Sensing by Gut Microbiota: Targeting Gut Peptides

Frontiers
There are more than 2 billion overweight and obese individuals worldwide, surpassing for the first time, the number of people affected by undernutrition.
9 months ago

Le Pen puts forward 'ghost' contender and convicted hostage-taker among candidates in election

The Telegraph
The hard-Right National Rally tries to control damage after embarrassing material of some members emerged days before second round of...
5 months ago

Short-chain fatty acids, secondary bile acids and indoles: gut microbial metabolites with effects on enteroendocrine cell function and their potential as therapies for metabolic disease

Frontiers
This review will focus on the activation mechanisms of glucagon-like peptide-1 releasing enteroendocrine cells by the three main bacterial metabolites produced...
9 months ago

Bariatric surgery for diabetic comorbidities: A focus on hepatic, cardiac and renal fibrosis

Frontiers
Continuously rising trends in diabetes render this disease spectrum an epidemic proportion worldwide. As the disease progresses, the pathological effects of...
9 months ago

Gut microbiota: The key to the treatment of metabolic syndrome in traditional Chinese medicine – a case study of diabetes and nonalcoholic fatty liver disease

Frontiers
Metabolic syndrome mainly includes obesity, type 2 diabetes (T2DM), alcoholic fatty liver (NAFLD) and cardiovascular diseases. According to the ancient...
9 months ago

New insights into the inter-organ crosstalk mediated by ChREBP

Frontiers
Carbohydrate response element binding protein (ChREBP) is a glucose responsive transcription factor recognized by its critical role in the...
21 months ago

Aberrant Gut-To-Brain Signaling in Irritable Bowel Syndrome - The Role of Bile Acids

Frontiers
Functional bowel disorders such as irritable bowel syndrome (IBS) are common, multifactorial and have a major impact on the quality of life of individuals...
10 months ago

Identification of chikusetsusaponin IVa as a novel lysine-specific demethylase 1 inhibitor that ameliorates high fat diet-induced MASLD in mice

Nature
Diet-induced metabolic dysfunction steatotic liver disease (MASLD) is also called as non-alcoholic fatty liver disease (NAFLD) with limited...
2 weeks ago

Balancing Herbal Medicine and Functional Food for Prevention and Treatment of Cardiometabolic Diseases through Modulating Gut Microbiota

Frontiers
It has become apparent that gut microbiota is closely associated with cardiometabolic diseases (CMDs), and alteration in microbiome compositions is also...
10 months ago

Probiotics, Pre-biotics and Synbiotics in the Treatment of Pre-diabetes: A Systematic Review of Randomized Controlled Trials

Frontiers
Objectives: This study aimed to review the data from randomized controlled trials (RCTs) and identify evidence for microbiota's role and use of probiotics,...
10 months ago